| 别名 | Substance-P receptor |
| 基因名称 | Endogenous |
| 蛋白名称 | TACR1 |
| 推荐应用 | |
| 反应物种 | NK-1R |
| 存储缓冲液 | WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Gene Link | TACR1;NK1R;TAC1R;Substance-P receptor;SPR;NK-1 receptor;NK-1R;Tachykinin receptor 1 |
| Human Swissprot No. | 6869 |
| Mouse Gene ID | P25103 |
| Mouse Swissprot No. | 21336 |
| Rat Gene ID | 24807 |
| Rat Swissprot No. | P14600 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 46kD |
| 预测分子量 | WB,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 46kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008], |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 功能 | Function:This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.,online information:Tachykinin entry,similarity:Belongs to the G-protein coupled receptor 1 family., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织表达 | Brain,G-protein coupled receptors,Lung,Placenta, |
| 研究领域 | >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction |
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