| 别名 | Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) |
| 基因名称 | Endogenous |
| 蛋白名称 | MYH10 |
| 推荐应用 | |
| 反应物种 | MYH10 |
| 存储缓冲液 | IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Swissprot No. | 4628 |
| Mouse Gene ID | P35580 |
| Mouse Swissprot No. | 77579 |
| Rat Gene ID | 79433 |
| Rat Swissprot No. | Q9JLT0 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 229kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 229kD |
| 同种型 | Rabbit |
| 细胞定位 | Cell projection, lamellipodium . Colocalizes with MCC at the leading edge of migrating cells. |
| 功能 | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cell projection, lamellipodium . Colocalizes with MCC at the leading edge of migrating cells. |
| 组织表达 | Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum. |
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