| 别名 | Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) |
| 基因名称 | Endogenous |
| 蛋白名称 | VAMP2 SYB2 |
| 推荐应用 | |
| 反应物种 | VAMP2 |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Swissprot No. | 6844 |
| Mouse Gene ID | P63027 |
| Mouse Swissprot No. | 22318 |
| Rat Gene ID | 24803 |
| Rat Swissprot No. | P63045 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 13kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 13kD |
| 同种型 | Rabbit |
| 细胞定位 | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell membrane . Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). . |
| 功能 | Involved in the targeting and/or fusion of transport vesicles to their target membrane (By similarity). Major SNARE protein of synaptic vesicles which mediates fusion of synaptic vesicles to release neurotransmitters. Essential for fast vesicular exocytosis and activity-dependent neurotransmitter release as well as fast endocytosis that mediates rapid reuse of synaptic vesicles (By similarity) . Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type IV membrane protein . Cell membrane . Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651). . |
| 组织表达 | Nervous system and skeletal muscle. |