| 别名 | Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36) |
| 基因名称 | Endogenous |
| 蛋白名称 | SCARB1 CD36L1 CLA1 |
| 推荐应用 | |
| 反应物种 | SCARB1 |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Swissprot No. | 949 |
| Mouse Gene ID | Q8WTV0 |
| Mouse Swissprot No. | 20778 |
| Rat Gene ID | 25073 |
| Rat Swissprot No. | P97943 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 61kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 80kD |
| 同种型 | Rabbit |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein. Membrane, caveola ; Multi-pass membrane protein. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. |
| 功能 | Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells . Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux . Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity . ; (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry . Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate . ; (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus. ; (Microbial infection) Facilitates the entry of human coronavirus SARS-CoV-2 by acting as an entry cofactor through HDL binding. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein. Membrane, caveola ; Multi-pass membrane protein. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. |
| 组织表达 | Widely expressed. |
周一至周日 8:00-18:00
