| 别名 | Acetyl-coenzyme A synthetase, cytoplasmic (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme) |
| 基因名称 | Endogenous |
| 蛋白名称 | ACSS2 ACAS2 |
| 推荐应用 | |
| 反应物种 | ACSS2 |
| 存储缓冲液 | WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Swissprot No. | 55902 |
| Mouse Gene ID | Q9NR19 |
| Mouse Swissprot No. | 60525 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 79kD |
| 预测分子量 | WB,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 79kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009], |
| 细胞定位 | Cytoplasm, cytosol . |
| 功能 | Catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,Function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm, cytosol . |
| 组织表达 | Blood,Melanoma,Muscle,Platelet,Skin,Tongue, |
| 研究领域 | >>Glycolysis / Gluconeogenesis;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Propanoate metabolism;>>Metabolic pathways;>>Carbon metabolism |