| 别名 | StAR-related lipid transfer protein 4;START domain-containing protein 4;StARD4; |
| 基因名称 | Endogenous |
| 蛋白名称 | STARD4 |
| 推荐应用 | |
| 反应物种 | STARD4 |
| 存储缓冲液 | WB 1:1000-5000;ICC/IF 1:100-300 |
| Human Gene Link | STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4; |
| Human Swissprot No. | 134429 |
| Mouse Gene ID | Q96DR4 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 预测分子量 | WB,IF,ICC |
| 运输及保存条件 | Protein A |
| 宿主 | 23kD |
| 同种型 | Rabbit |
| 背景介绍 | Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008] |
| 功能 | Involved in the intracellular transport of cholesterol. Binds cholesterol or other sterols. {ECO:0000269|PubMed:18403318}. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
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