| 别名 | Methionine aminopeptidase 1 (MAP 1) (MetAP 1) (Peptidase M 1) |
| 基因名称 | Endogenous |
| 蛋白名称 | METAP1 KIAA0094 |
| 推荐应用 | |
| 反应物种 | Methionyl Aminopeptidase 1 |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | AMPM1 HUMAN,MAP 1,MAP1A,MetAP 1,MetAP1A,Methionine aminopeptidase 1,Peptidase M 1, |
| Human Swissprot No. | 23173 |
| Mouse Gene ID | P53582 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 42kDa |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 42kDa |
| 同种型 | Rabbit |
| 背景介绍 | catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,function:Removes the amino-terminal methionine from nascent proteins.,function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family., |
| 细胞定位 | Cytoplasm . |
| 功能 | Catalytic activity:Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.,cofactor:Binds 1 sodium ion per subunit. The sodium ion has a structural role.,cofactor:Binds 2 cobalt ions per subunit.,cofactor:Binds 2 cobalt ions per subunit. The true nature of the physiological cofactor is under debate. The enzyme is also active with zinc, manganese or divalent iron ions.,Function:Removes the amino-terminal methionine from nascent proteins.,Function:Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.,similarity:Belongs to the peptidase M24A family., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm . |
| 组织表达 | Bone marrow,Placenta,Testis, |
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