| 别名 | OSBL1 |
| 基因名称 | Endogenous |
| 蛋白名称 | OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B |
| 推荐应用 | |
| 反应物种 | ORP1 |
| 存储缓冲液 | WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | Oxysterol-binding protein-related protein 1;ORP-1;OSBP-related protein 1; |
| Human Swissprot No. | 114876 |
| Mouse Gene ID | Q9BXW6 |
| Mouse Swissprot No. | 64291 |
| Rat Gene ID | 259221 |
| Rat Swissprot No. | Q8K4M9 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 105kDa |
| 预测分子量 | WB,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 105kDa |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. |
| 功能 | Function:Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with VAPA., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. |
| 组织表达 | Bone,Brain,Embryo,Epithelium,Kidney,Pancreas,Testicle, |
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