| 别名 | Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt) |
| 基因名称 | Endogenous |
| 蛋白名称 | TSFM |
| 推荐应用 | |
| 反应物种 | TSFM |
| 存储缓冲液 | WB 1:1000-5000;ICC/IF 1:100-300 |
| Human Gene Link | TSFM;Elongation factor Ts, mitochondrial ;EF-Ts;EF-TsMt; |
| Human Swissprot No. | 10102 |
| Mouse Gene ID | P43897 |
| Mouse Swissprot No. | 66399 |
| Rat Swissprot No. | Q9QYU2 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 预测分子量 | WB,IF,ICC |
| 运输及保存条件 | Protein A |
| 宿主 | 36kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a mitochondrial translation elongation factor. The encoded protein is an enzyme that catalyzes the exchange of guanine nucleotides on the translation elongation factor Tu during the elongation step of mitchondrial protein translation. Mutations in this gene are associated with combined oxidative phosphorylation deficiency-3 syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010] |
| 细胞定位 | Mitochondrion. |
| 功能 | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. {ECO:0000255|HAMAP-Rule:MF_03135, ECO:0000269|PubMed:27677415}. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Mitochondrion. |
| 组织表达 | Expressed in all tissues, with the highest levels of expression in skeletal muscle, liver and kidney. |
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