| 别名 | Kelch-like protein 6 |
| 基因名称 | Endogenous |
| 蛋白名称 | KLHL6 |
| 推荐应用 | |
| 反应物种 | KLHL6 |
| 存储缓冲液 | WB 1:1000-5000;ICC/IF 1:100-300;IP 1:50-100 |
| Human Gene Link | KLHL6;Kelch-like protein 6; |
| Human Swissprot No. | 89857 |
| Mouse Gene ID | Q8WZ60 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 预测分子量 | WB,IF,ICC,IP |
| 运输及保存条件 | Protein A |
| 宿主 | 68kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a member of the kelch-like (KLHL) family of proteins, which is involved in B-lymphocyte antigen receptor signaling and germinal-center B-cell maturation. The encoded protein contains an N-terminal broad-complex, tramtrack and bric a brac (BTB) domain that facilitates protein binding and dimerization, a BTB and C-terminal kelch (BACK) domain, and six C-terminal kelch repeat domains. Naturally occurring mutations in this gene are associated with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017] |
| 功能 | Involved in B-lymphocyte antigen receptor signaling and germinal center formation. {ECO:0000250}. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 组织表达 | Found in germinal center B-cells. {ECO:0000269|PubMed:12617994}. |
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