| 基因名称 | Endogenous |
| 蛋白名称 | wnt3a |
| 推荐应用 | |
| 反应物种 | Wnt3a |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Gene Link | MGC119418;MGC119419;MGC119420;Protein Wnt 3a Precursor;Protein Wnt-3a;Wingless type MMTV integration site family member 3A;Wnt 3a;wnt3a;WNT3A protein;WNT3A_HUMAN. |
| Human Swissprot No. | 89780 |
| Mouse Gene ID | P56704 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 39kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 39kD |
| 同种型 | Rabbit |
| 背景介绍 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Secreted, extracellular space, extracellular matrix . Secreted . |
| 功能 | Function:Ligand for members of the frizzled family of seven transmembrane receptors.,Function:Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.,similarity:Belongs to the Wnt family.,subunit:Interacts with PORCN.,tissue specificity:Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Secreted, extracellular space, extracellular matrix . Secreted . |
| 组织表达 | Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate. |
| 研究领域 | >>mTOR signaling pathway;>>Wnt signaling pathway;>>Hippo signaling pathway;>>Signaling pathways regulating pluripotency of stem cells;>>Melanogenesis;>>Cushing syndrome;>>Alzheimer disease;>>Pathways of neurodegeneration - multiple diseases;>>Human papillomavirus infection;>>Pathways in cancer;>>Proteoglycans in cancer;>>MicroRNAs in cancer;>>Basal cell carcinoma;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer |
周一至周日 8:00-18:00
