| 别名 | Anoctamin-1 |
| 基因名称 | Endogenous |
| 蛋白名称 | ANO1 |
| 推荐应用 | |
| 反应物种 | TMEM16A |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | ANO1;DOG1;ORAOV2;TAOS2;TMEM16A;Anoctamin-1;Discovered on gastrointestinal stromal tumors protein 1;Oral cancer overexpressed protein 2;Transmembrane protein 16A;Tumor-amplified and overexpressed sequence 2 |
| Human Swissprot No. | 55107 |
| Mouse Gene ID | Q5XXA6 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 114kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 130kD |
| 同种型 | Rabbit |
| 背景介绍 | domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle., |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. . |
| 功能 | Domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,Function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. . |
| 组织表达 | Broadly expressed with higher levels in liver, skeletal muscle and gastrointestinal muscles. |
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