| 别名 | Protein fosB |
| 基因名称 | Endogenous |
| 蛋白名称 | FOSB |
| 推荐应用 | |
| 反应物种 | Fos B |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Gene Link | FOSB;G0S3;Protein fosB;G0/G1 switch regulatory protein 3 |
| Human Swissprot No. | 2354 |
| Mouse Gene ID | P53539 |
| Mouse Swissprot No. | 14282 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 36kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 38kD,48kD |
| 同种型 | Rabbit |
| 背景介绍 | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Nucleus . |
| 功能 | Function:FosB interacts with Jun proteins enhancing their DNA binding activity.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Nucleus . |
| 组织表达 | [Isoform 11]: Expressed in the nucleus accumbens of the striatum (at protein level). |
| 研究领域 | >>Osteoclast differentiation;>>IL-17 signaling pathway;>>Cocaine addiction;>>Amphetamine addiction;>>Alcoholism |
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