| 别名 | Peptidyl-prolyl cis-trans isomerase F mitochondrial |
| 基因名称 | Endogenous |
| 蛋白名称 | PPIF |
| 推荐应用 | |
| 反应物种 | Cyclophilin F |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | PPIF;CYP3;Peptidyl-prolyl cis-trans isomerase F;mitochondrial;PPIase F;Cyclophilin F;Rotamase F |
| Human Swissprot No. | 10105 |
| Mouse Gene ID | P30405 |
| Mouse Swissprot No. | 105675 |
| Rat Gene ID | 282819 |
| Rat Swissprot No. | P29117 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 22kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 18kD |
| 同种型 | Rabbit |
| 背景介绍 | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008], |
| 细胞定位 | Mitochondrion matrix . |
| 功能 | Catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,Function:PPIases accelerate the folding of proteins.,Function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Mitochondrion matrix . |
| 组织表达 | Blood,Cord blood,Ovary, |
| 研究领域 | >>Calcium signaling pathway;>>cGMP-PKG signaling pathway;>>Neutrophil extracellular trap formation;>>Alzheimer disease;>>Parkinson disease;>>Huntington disease;>>Spinocerebellar ataxia;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Toxoplasmosis;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy |
周一至周日 8:00-18:00
