| 别名 | Fos-related antigen 1 |
| 基因名称 | Endogenous |
| 蛋白名称 | FOSL1 |
| 推荐应用 | |
| 反应物种 | FRA1 |
| 存储缓冲液 | IHC 1:1000-1:4000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | FOSL1;FRA1;Fos-related antigen 1;FRA-1 |
| Human Swissprot No. | 8061 |
| Mouse Gene ID | P15407 |
| Mouse Swissprot No. | 14283 |
| Rat Gene ID | 25445 |
| Rat Swissprot No. | P10158 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 29kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 40kD |
| 同种型 | Rabbit |
| 背景介绍 | The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014], |
| 细胞定位 | Nucleus . |
| 功能 | similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG, Kappa |
| 细胞定位 | Nucleus . |
| 组织表达 | Blood,Endothelial cell,Kidney,Skin, |
| 研究领域 | >>Wnt signaling pathway;>>Osteoclast differentiation;>>IL-17 signaling pathway;>>Human T-cell leukemia virus 1 infection |
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