| 别名 | Chorionic somatomammotropin hormone-like 1;Chorionic somatomammotropin-like;Lactogen-like; |
| 基因名称 | Endogenous |
| 蛋白名称 | CSHL1;CSHP1;CSL |
| 推荐应用 | |
| 反应物种 | CSHL1 |
| 存储缓冲液 | WB 1:1000-5000;IHC 1:100-300 |
| Human Gene Link | CSHL1;CSHP1;CSL;Chorionic somatomammotropin hormone-like 1 ;Chorionic somatomammotropin-like;Lactogen-like; |
| Human Swissprot No. | 1444 |
| Mouse Gene ID | Q14406 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 预测分子量 | WB,IHC |
| 运输及保存条件 | Protein A |
| 宿主 | 24kD |
| 同种型 | Rabbit |
| 背景介绍 | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| 细胞定位 | Secreted. |
| 功能 | May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation. {ECO:0000269|PubMed:8083227}. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Secreted. |
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