| 别名 | Homeobox protein CDX-2 |
| 基因名称 | Endogenous |
| 蛋白名称 | CDX2 |
| 推荐应用 | |
| 反应物种 | CDX2 |
| 存储缓冲液 | IHC 1:500-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | CDX2;CDX3;Homeobox protein CDX-2;CDX-3;Caudal-type homeobox protein 2 |
| Human Swissprot No. | 1045 |
| Mouse Gene ID | Q99626 |
| Mouse Swissprot No. | 12591 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 34kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 38kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012], |
| 细胞定位 | Nucleus . |
| 功能 | Function:Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.,PTM:Phosphorylation of Ser-60 mediates the transactivation capacity.,similarity:Belongs to the Caudal homeobox family.,similarity:Contains 1 homeobox DNA-binding domain., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Nucleus . |
| 组织表达 | Detected in small intestine, colon and pancreas. |
| 研究领域 | >>Gastric cancer |
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