| 别名 | Ribonucleoside-diphosphate reductase large subunit (Ribonucleoside-diphosphate reductase subunit M1) (Ribonucleotide reductase large subunit) |
| 基因名称 | Endogenous |
| 蛋白名称 | RRM1 RR1 |
| 推荐应用 | |
| 反应物种 | RRM1 |
| 存储缓冲液 | WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Swissprot No. | 6240 |
| Mouse Gene ID | P23921 |
| Mouse Swissprot No. | 20133 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 90kD |
| 预测分子量 | WB,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 90kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
| 细胞定位 | Cytoplasm |
| 功能 | Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm |
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