| 别名 | RSK3 |
| 基因名称 | Endogenous |
| 蛋白名称 | RPS6KA2 MAPKAPK1C RSK3 |
| 推荐应用 | |
| 反应物种 | RSK3 |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Gene Link | Ribosomal protein S6 kinase alpha-2;S6K-alpha-2;90 kDa ribosomal protein S6 kinase 2;p90-RSK 2;p90RSK2;MAP kinase-activated protein kinase 1c;MAPK-activated protein kinase 1c;MAPKAP kinase 1c;MAPKAPK-1c;Ribosomal S6 kinase 3;RSK-3;pp90RSK3; |
| Human Swissprot No. | 6196 |
| Mouse Gene ID | Q15349 |
| Mouse Swissprot No. | 20112 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 83kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 90kD |
| 同种型 | Rabbit |
| 背景介绍 | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle., |
| 细胞定位 | Nucleus . Cytoplasm . |
| 功能 | protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, phosphorylation, |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG, Kappa |
| 细胞定位 | Nucleus . Cytoplasm . |
| 组织表达 | Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate. |
| 研究领域 | >>MAPK signaling pathway;>>Oocyte meiosis;>>mTOR signaling pathway;>>Thermogenesis;>>Long-term potentiation;>>Neurotrophin signaling pathway;>>Progesterone-mediated oocyte maturation;>>Insulin resistance;>>Yersinia infection;>>Chemical carcinogenesis - receptor activation |
周一至周日 8:00-18:00
