| 别名 | T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56) |
| 基因名称 | Endogenous |
| 蛋白名称 | TBR1 |
| 推荐应用 | |
| 反应物种 | TBR1 |
| 存储缓冲液 | IHC 1:200-1000;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000; |
| Human Swissprot No. | 10716 |
| Mouse Gene ID | Q16650 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 74kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 74kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015], |
| 细胞定位 | Nuclear |
| 功能 | Function:Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Brain., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Nuclear |
| 组织表达 | Brain. |
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