| 别名 | Intraflagellar transport protein 88 homolog (Recessive polycystic kidney disease protein Tg737 homolog) (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) |
| 基因名称 | Endogenous |
| 蛋白名称 | IFT88 TG737 TTC10 |
| 推荐应用 | |
| 反应物种 | IFT88 |
| 存储缓冲液 | WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Swissprot No. | 8100 |
| Mouse Gene ID | Q13099 |
| Mouse Swissprot No. | 21821 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 94kD |
| 预测分子量 | WB,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 94kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017] |
| 细胞定位 | Cytoplasm |
| 功能 | Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment. |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm |
| 组织表达 | Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas. |
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