| 别名 | Tubulin beta chain (Tubulin beta-5 chain) |
| 基因名称 | Endogenous |
| 蛋白名称 | TUBB |
| 推荐应用 | |
| 反应物种 | Tubulin β |
| 存储缓冲液 | IHC 1:2000-1:10000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| Human Gene Link | Tubulin beta chain (Tubulin beta-5 chain) |
| Human Swissprot No. | 203068 |
| Mouse Gene ID | P07437 |
| Rat Swissprot No. | P69897 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 50kD |
| 预测分子量 | WB,IHC,IF,IP,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 50kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014], |
| 细胞定位 | Cytoplasm |
| 功能 | Domain:The highly acidic C-terminal region may bind cations such as calcium.,Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,online information:Tubulin entry,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,tissue specificity:Ubiquitously expressed with highest levels in spleen, thymus and immature brain., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm |
| 组织表达 | Ubiquitously expressed with highest levels in spleen, thymus and immature brain. |
| 研究领域 | >>Phagosome;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection |
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