| 别名 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial |
| 基因名称 | Endogenous |
| 蛋白名称 | NDUFS3 |
| 推荐应用 | |
| 反应物种 | NDUFS3 |
| 存储缓冲液 | IHC 1:200-1:1000;WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | NDUFS3;NADH dehydrogenase [ubiquinone] iron-sulfur protein 3;mitochondrial;Complex I-30kD;CI-30kD;NADH-ubiquinone oxidoreductase 30 kDa subunit |
| Human Swissprot No. | 4722 |
| Mouse Gene ID | O75489 |
| Mouse Swissprot No. | 68349 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 30kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 30kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009], |
| 细胞定位 | Mitochondrion inner membrane |
| 功能 | Catalytic activity:NADH + acceptor = NAD(+) + reduced acceptor.,Catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol.,Function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I 30 kDa subunit family.,subunit:Mammalian complex I is composed of 45 different subunits., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Mitochondrion inner membrane |
| 组织表达 | Brain,Cajal-Retzius cell,Pituitary,Skin,Stomach mucosa,Uter |
| 研究领域 | >>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy |
周一至周日 8:00-18:00
