| 别名 | Early endosome antigen 1 |
| 基因名称 | Endogenous |
| 蛋白名称 | EEA1 |
| 推荐应用 | |
| 反应物种 | EEA1 |
| 存储缓冲液 | IHC 1:100-200;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000; |
| Human Gene Link | EEA1;ZFYVE2;Early endosome antigen 1;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2 |
| Human Swissprot No. | 8411 |
| Mouse Gene ID | Q15075 |
| Mouse Swissprot No. | 216238 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 162kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 162kD |
| 同种型 | Rabbit |
| 背景介绍 | disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| 细胞定位 | Cytoplasm |
| 功能 | Disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,Domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,Function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Cytoplasm |
| 组织表达 | Aorta,Cervix carcinoma,Fetal brain cortex,Skeletal muscle, |
| 研究领域 | >>Endocytosis;>>Phagosome;>>Tuberculosis |
周一至周日 8:00-18:00
