| 别名 | Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325) |
| 基因名称 | Endogenous |
| 蛋白名称 | CDH2 CDHN NCAD |
| 推荐应用 | |
| 反应物种 | N-cadherin |
| 存储缓冲液 | IHC 1:500-1:2000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000; |
| Human Gene Link | CDH2;CDHN;NCAD;Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD antigen CD325 |
| Human Swissprot No. | 1000 |
| Mouse Gene ID | P19022 |
| Mouse Swissprot No. | 12558 |
| Rat Gene ID | 83501 |
| Rat Swissprot No. | Q9Z1Y3 |
| 特异性 | Monoclonal |
| 稀释度 | Unmodified |
| 参考分子量 | 125kD |
| 预测分子量 | WB,IHC,IF,ELISA |
| 运输及保存条件 | Protein A |
| 宿主 | 130kD |
| 同种型 | Rabbit |
| 背景介绍 | This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015], |
| 细胞定位 | Membrane |
| 功能 | Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism.,similarity:Contains 5 cadherin domains.,subunit:Interacts with CDCP1., |
| 纯化 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Clonality | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 修饰类型 | IgG,Kappa |
| 细胞定位 | Membrane |
| 组织表达 | Brain,Epithelium,Liver, |
| 研究领域 | >>Cell adhesion molecules;>>Arrhythmogenic right ventricular cardiomyopathy |
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