| 别名 | CLH17, CLTCL2, KIAA0034, CLTC, Clathrin heavy chain 1, Clathrin heavy chain on chromosome 17, CLH-17 |
| 基因名称 | CLTC CLH17 CLTCL2 KIAA0034 |
| 蛋白名称 | Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000-1:10000;IHC-P 1:50-1:200 |
| 参考分子量 | MW(Observed):192kD |
| 预测分子量 | MW(Calculated):192kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Clathrin is a major protein component of the cytoplasmic face of intracellular organelles , called coated vesicles and coated pits. These specialized organelles are involved in the intracellular trafficking of receptors and endocytosis of a variety of macromolecules. The basic subunit of the clathrin coat is composed of three heavy chains and three light chains. |
| 细胞定位 | Cytoplasm |
| 功能 | Function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. ,online information:Clathrin entry ,similarity:Belongs to the clathrin heavy chain family. ,subcellular location:Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | Ubiquitous expression |