| 别名 | ZO1, TJP1, Tight junction protein 1, Tight junction protein ZO-1, Zona occludens protein 1, Zonula occludens protein 1 |
| 基因名称 | TJP1 ZO1 |
| 蛋白名称 | Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000;IHC-P 1:50-200 |
| 参考分子量 | MW(Observed):250kD |
| 预测分子量 | MW(Calculated):195kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Enables connexin binding activity and protein domain specific binding activity. Involved in several processes, including ameloblast differentiation; negative regulation of stress fiber assembly; and positive regulation of sprouting angiogenesis. Acts upstream of or within blastocyst formation and sensory perception of sound. Located in several cellular components, including apicolateral plasma membrane; bicellular tight junction; and intercellular canaliculus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human TJP1 (tight junction protein 1). |
| 细胞定位 | Cell membrane, Peripheral membrane protein, Cell junction, tight junction, gap junction, Cell projection, podosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Peripheral membrane protein, Cell junction, tight junction, gap junction, Cell projection, podosome. |
| 组织表达 | Intestine, Kidney, Lung epithelium, Colorectal carcinoma, Renal cell carcinoma, Lung adenocarcinoma |
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