| 别名 | Neurofilament light polypeptide;NF-L;68 kDa neurofilament protein;Neurofilament triplet L protein; |
| 基因名称 | NF-L |
| 蛋白名称 | Neurofilament light polypeptide;NF-L;Neurofilament triplet L protein;68 kDa neurofilament protein; |
| 推荐应用 | |
| 反应物种 | Rat（WB);Human,Mouse,Rat（IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4747 |
| Human Swissprot No. | P07196 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200; |
| 参考分子量 | MW(Observed):68kD |
| 预测分子量 | MW(Calculated):62kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008], |
| 细胞定位 | Cytoplasm |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | Brain, Spinal cord, Neurons, Neuroblastoma, Glioma, Medulloblastoma, Alzheimer's disease brain |
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