| 别名 | NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; |
| 基因名称 | TrkA |
| 蛋白名称 | TrkA |
| 推荐应用 | |
| 反应物种 | Mouse Rat(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P04629 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000;IHC 1:100-300 |
| 预测分子量 | 145kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning. |
| 细胞定位 | Membrane |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane |
| 组织表达 | Brain, Spinal cord, Neurons, Neuroblastoma, Glioma, Medulloblastoma, Alzheimer's disease brain |
