| 别名 | NGF;Beta-NGF;HSAN5;MGC161426;MGC161428;NGFB;proNGF; |
| 基因名称 | NGF |
| 蛋白名称 | NGF |
| 推荐应用 | |
| 反应物种 | Mouse Rat(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P01138 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000;IHC 1:100-300 |
| 预测分子量 | 27kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Nerve growth factor (NGF) is a small, secreted protein and member of the neurotrophin family of growth factors that promote neuronal cell survival and differentiation. Producing cells release NGF that bind and activate TrkA high affinity receptors to mediate NGF-driven signaling. NGF also binds to a low affinity p75 (NTR) receptors, which belong to the death receptor family. |
| 细胞定位 | Secreted |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted |
| 组织表达 | Brain, Spinal cord, Heart, Neuroblastoma, Glioma, Medulloblastoma, Alzheimer's disease brain |
