| 别名 | EC 2.7.11.1; SGK; SGK1; Serum/glucocorticoid-regulated kinase; Sgk; Sgk1; kinase SGK; |
| 基因名称 | SGK1 |
| 蛋白名称 | SGK1 |
| 推荐应用 | |
| 反应物种 | Mouse Rat(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | O00141 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000;IHC 1:100-300 |
| 预测分子量 | 57kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation. |
| 细胞定位 | Cytoplasm, Nucleus |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus |
| 组织表达 | Ubiquitous expression |