| 别名 | CDK5; CRK6; Cell division protein kinase 5; EC 2.7.11.22; PSSALRE; TAU protein kinase II catalytic subunit; TPKII catalytic subunit; Tau protein kinase II catalytic subunit; kinase Cdk5; |
| 基因名称 | CDK5 |
| 蛋白名称 | CDK5 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q00535 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:5000;IHC 1:100-300 |
| 预测分子量 | 33kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta-catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation. |
| 细胞定位 | Cytoplasm, Nucleus |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus |
| 组织表达 | Brain, Spinal cord, Neurons, Neuroblastoma, Glioma, Medulloblastoma, Alzheimer's disease brain |
周一至周日 8:00-18:00
