| 别名 | CDC47 homolog; P1.1-MCM3; MCM7; CDC47; MCM2; P1CDC47; P85MCM; PNAS146; PPP1R104; |
| 基因名称 | MCM7 |
| 蛋白名称 | MCM7 |
| 推荐应用 | |
| 反应物种 | Human Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P33993 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000;IHC 1:100-300 |
| 预测分子量 | 81kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. |
| 细胞定位 | Nucleus |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus |
| 组织表达 | Testis, Bone marrow, Intestinal epithelium, Breast carcinoma, Lung cancer, Colorectal carcinoma, Ovarian carcinoma |
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