| 别名 | Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, Lanimostim, Proteoglycan macrophage colony-stimulating factor, PG-M-CSF, CSF1 |
| 基因名称 | CSF1 |
| 蛋白名称 | Macrophage colony-stimulating factor 1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P09603 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:300 |
| 预测分子量 | 20kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The protein encoded by this gene is a cytokine that controls the production , differentiation , and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer , and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. |
| 细胞定位 | Cytoplasm, Secreted |
| 功能 | Function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production , differentiation , and function of 2 related white cell populations of the blood , the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses , bone metabolism , lipoproteins clearance , fertility and pregnancy. ,PTM:Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Secreted |
| 组织表达 | Bone marrow, Spleen, Liver, Breast carcinoma, Lung cancer, Pancreatic carcinoma, Ovarian carcinoma |
周一至周日 8:00-18:00
