| 别名 | Stromal cell-derived factor 1; SDF-1; hSDF-1; IRH; hIRH; PBSF; CXCL12; SDF1; SDF1A; SDF1B; |
| 基因名称 | SDF1 |
| 蛋白名称 | SDF1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P48061 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:300 |
| 预测分子量 | 11kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. |
| 细胞定位 | Cytoplasm, Secreted |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Secreted |
| 组织表达 | Bone marrow, Spleen, Lymph node, Liver, Breast carcinoma, Lung cancer, Pancreatic carcinoma |
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