| 别名 | Tbr2, Eomes, Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2 |
| 基因名称 | EOMES |
| 蛋白名称 | Eomesodermin homolog |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 8230 |
| Human Swissprot No. | O95936 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:300 |
| 参考分子量 | MW(Observed):70-80kD |
| 预测分子量 | MW(Calculated):73kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. |
| 细胞定位 | Nucleus |
| 功能 | similarity:Contains 1 T-box DNA-binding domain. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus |
| 组织表达 | Spleen, Thymus, Lymph node, T cells, Melanoma, Lymphoma, Colorectal carcinoma |
周一至周日 8:00-18:00
