| 别名 | FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1; |
| 基因名称 | FADD |
| 蛋白名称 | FADD |
| 推荐应用 | |
| 反应物种 | Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | Q61160 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:300 |
| 预测分子量 | 28kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. |
| 细胞定位 | Cytoplasm |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | Spleen, Thymus, Bone marrow, Lymphoma, Leukemia, Breast carcinoma, Lung cancer |
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