| 别名 | HIRS1; Insulin receptor substrate 1; IRS 1; IRS1; |
| 基因名称 | IRS1 |
| 蛋白名称 | IRS1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Swissprot No. | P35568 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:300 |
| 预测分子量 | 170kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | IRS1 is one of the major substrates of the insulin receptor kinase. May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. |
| 细胞定位 | Cytoplasm |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm |
| 组织表达 | Liver, Muscle, Adipose tissue, Breast carcinoma, Colorectal carcinoma, Pancreatic carcinoma, Prostate carcinoma |
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