| 别名 | GH-binding protein; GHBP; GHR; Serum binding protein; Somatotropin receptor; |
| 基因名称 | Growth hormone receptor |
| 蛋白名称 | Growth hormone receptor |
| 推荐应用 | |
| 反应物种 | Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2690 |
| Human Swissprot No. | P10912 |
| Mouse Gene ID | 14600 |
| Mouse Swissprot No. | P16882 |
| Rat Gene ID | 25235 |
| Rat Swissprot No. | P16310 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 140 kDa |
| 预测分子量 | MW(Calculated): 72 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling. |
| 细胞定位 | Secreted. Cell membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted. Cell membrane. |
| 组织表达 | Liver, Adipose tissue, Muscle, Hepatocellular carcinoma, Adipocytic tumor |
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