| 别名 | CYPIIIA3; CYPIIIA4; Cytochrome P450 3A3; Cytochrome P450 HLp; Cytochrome P450 NF-25; Cytochrome P450-PCN1; Nifedipine oxidase; |
| 基因名称 | Cytochrome P450 3A4 |
| 蛋白名称 | Cytochrome P450 3A4 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1576 |
| Human Swissprot No. | P08684 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:5000 |
| 参考分子量 | MW(Observed): 50 kDa |
| 预测分子量 | MW(Calculated): 57 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide. |
| 细胞定位 | Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Endoplasmic reticulum membrane, Microsome membrane, Single-pass membrane protein. |
| 组织表达 | Liver, Small intestine, Hepatocellular carcinoma, Intestinal adenocarcinoma, Lung cancer |
周一至周日 8:00-18:00
