| 别名 | Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase; ZAP70; SRK; |
| 基因名称 | ZAP70 |
| 蛋白名称 | ZAP70 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 7535 |
| Human Swissprot No. | P43403 |
| Mouse Gene ID | 22637 |
| Mouse Swissprot No. | P43404 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed): 70 kDa |
| 预测分子量 | MW(Calculated): 70 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck. |
| 细胞定位 | Cell membrane, Cytoplasm, Peripheral membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cytoplasm, Peripheral membrane protein. |
| 组织表达 | Spleen, Lymph node, Thymus, T cells, Lymphoma, Leukemia, Thymoma |
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