| 别名 | Beta-secretase 1; Aspartyl protease 2; ASP2; Asp 2; Memapsin-2; BACE1; BACE; |
| 基因名称 | BACE1 |
| 蛋白名称 | BACE1 |
| 推荐应用 | |
| 反应物种 | Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 23621; |
| Human Swissprot No. | P56817 |
| Mouse Gene ID | 23821; |
| Mouse Swissprot No. | P56818 |
| Rat Gene ID | 29392; |
| Rat Swissprot No. | P56819; |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 70 kDa |
| 预测分子量 | MW(Calculated): 56 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. |
| 细胞定位 | Membrane , Cytoplasm |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane , Cytoplasm |
| 组织表达 | Brain, Neurons, Alzheimer's disease brain, Glioma, Neuroblastoma |
周一至周日 8:00-18:00
