| 别名 | FKBP 12; FKBP 1A; FKBP1; FKBP12 Exip3; FKBP12C; fkbp1a; Immunophilin FKBP12; PKC12; PPIase FKBP1A; Rotamase; |
| 基因名称 | FKBP12 |
| 蛋白名称 | FKBP12 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2280; |
| Human Swissprot No. | P62942 |
| Mouse Gene ID | 14225 |
| Mouse Swissprot No. | P26883 |
| Rat Gene ID | 25639 |
| Rat Swissprot No. | Q62658; |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:5000 |
| 参考分子量 | MW(Observed): 12 kDa |
| 预测分子量 | MW(Calculated): 12 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| 细胞定位 | Cytoplasm , cytosol . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm , cytosol . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
周一至周日 8:00-18:00
