| 别名 | APPS; Cathepsin B heavy chain; Cathepsin B1; CathepsinB; CPSB; CTSB; cysteine protease; Preprocathepsin B; |
| 基因名称 | Cathepsin B |
| 蛋白名称 | Cathepsin B |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1508; |
| Human Swissprot No. | P07858 |
| Mouse Gene ID | 13030; |
| Mouse Swissprot No. | P10605 |
| Rat Swissprot No. | P00787; |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 38 kDa |
| 预测分子量 | MW(Calculated): 38 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. |
| 细胞定位 | Lysosome . Melanosome . Secreted , extracellular space . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity) . . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Lysosome . Melanosome . Secreted , extracellular space . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) . Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells (By similarity) . . |
| 组织表达 | Liver, Spleen, Kidney, Hepatocellular carcinoma, Lymphoma, Melanoma, Breast carcinoma |
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