| 别名 | FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A; |
| 基因名称 | FOXA1 |
| 蛋白名称 | FOXA1 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3169 |
| Human Swissprot No. | P55317 |
| Mouse Gene ID | 15375 |
| Mouse Swissprot No. | P35582 |
| Rat Gene ID | 25098 |
| Rat Swissprot No. | P23512 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 49 kDa |
| 预测分子量 | MW(Calculated): 49 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. |
| 细胞定位 | Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. |
| 组织表达 | Liver, Pancreas, Prostate, Breast, Hepatocellular carcinoma, Prostate carcinoma, Breast carcinoma |
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