| 别名 | CLGI; Collagenase inhibitor; EPA; EPO; HCI; Metalloproteinase inhibitor 1; TIMP; TIMP1; |
| 基因名称 | TIMP1 |
| 蛋白名称 | TIMP1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 7076; |
| Human Swissprot No. | P01033 |
| Mouse Gene ID | 21857; |
| Mouse Swissprot No. | P12032 |
| Rat Gene ID | 116510; |
| Rat Swissprot No. | P30120; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:1000 |
| 参考分子量 | MW(Observed): 26 kDa |
| 预测分子量 | MW(Calculated): 23 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | TIMP1 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. |
| 细胞定位 | Secreted . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted . |
| 组织表达 | Ubiquitous expression |