| 别名 | INSULYSIN; Insulin degrading enzyme; IDE; |
| 基因名称 | IDE |
| 蛋白名称 | IDE |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3416 |
| Human Swissprot No. | P14735 |
| Mouse Swissprot No. | Q9JHR7 |
| Rat Gene ID | 25700 |
| Rat Swissprot No. | P35559 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 118 kDa |
| 预测分子量 | MW(Calculated): 118 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. |
| 细胞定位 | Cytoplasm, Cell membrane, Secreted. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Cell membrane, Secreted. |
| 组织表达 | Ubiquitous expression |
周一至周日 8:00-18:00
