| 别名 | Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A |
| 基因名称 | Phospho-GSK3 (alpha + beta)(Y216 + Y279) |
| 蛋白名称 | Phospho-GSK3 (alpha + beta)(Y216 + Y279) |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2931; |
| Human Swissprot No. | P49840 |
| Mouse Gene ID | 606496; |
| Mouse Swissprot No. | Q2NL51; |
| Rat Gene ID | 50686; |
| Rat Swissprot No. | P18265; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 51kDa,46kDa |
| 预测分子量 | MW(Calculated): 47,51 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane. |
| 组织表达 | Ubiquitous expression |