| 别名 | GRM2; Glutamate receptor homolog; GPRC1B; MGlu2; Metabotropic; GLUR2; MGLUR2; |
| 基因名称 | mGluR2 |
| 蛋白名称 | mGluR2 |
| 推荐应用 | |
| 反应物种 | Mouse Rat(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2912; |
| Human Swissprot No. | Q14416 |
| Mouse Gene ID | 108068; |
| Mouse Swissprot No. | Q14BI2 |
| Rat Gene ID | 24415; |
| Rat Swissprot No. | P31421; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed): 95,200 kDa |
| 预测分子量 | MW(Calculated): 96 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction , synapse . Cell projection , dendrite . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction , synapse . Cell projection , dendrite . |
| 组织表达 | Brain, Spinal cord, Neurons, Glioma, Neuroblastoma, Alzheimer's disease brain |
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