| 别名 | CASP14; Caspase-14; Caspase 14; MICE; CASP-14; |
| 基因名称 | Caspase-14 |
| 蛋白名称 | Caspase-14 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 23581; |
| Human Swissprot No. | P31944 |
| Mouse Gene ID | 12365 |
| Mouse Swissprot No. | O89094; |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 28 kDa |
| 预测分子量 | MW(Calculated): 28 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. May also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes. |
| 细胞定位 | Cytoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus. |
| 组织表达 | Skin, Epidermis, Hair follicle, Squamous cell carcinoma, Basal cell carcinoma |